Adipose-derived stem cells combined with 3D printing technology recreated as possible

As early as 1986, American scientists invented the world's first 3D printer. However, its technology has been widely known in recent years. With the development of the times, 3D printing has been more widely used in people's daily lives. The role of 3D printing is not only to create models for objects such as plastics and metals, but also to print drugs and even combine them with biological tissues to transform the traditional human medical model.

Imagine if you have an organ or tissue in your body and you are worried about finding scarce donor organs. At this time, the hospital used 3D printing technology to print out a brand new organ transplanted into your body and replace the damaged organ like replacing old parts on a machine.

In fact, with the advancement of science and technology, scenes that appear to only appear in science fiction and movies are no longer a fantasy. For example, extracting your own fat as an excellent consumable, you can use 3D printing technology to recreate your body and organs.

Deep cryogenic liquid nitrogen canisters of “frozen” adipose stem cells taken in Sichuan stem cell bank

Why is it fat? This is because fat tissue is rich in stem cells and has been used in research in the field of regenerative medicine. It not only has amazing effects in terms of skin beauty, immunity enhancement, and aging of resistant organs, but also can be used as a biological resource. The cryogenic cryogenic liquid nitrogen environment is stored for a long period of time. Once the organ is damaged, it can be removed from the "ice seal" for organ reconstruction.

However, in order for fat stem cells to truly act on the human body, they must also form a rational structure. 3D printing technology is undoubtedly an outstanding stylist in this area.

The early start of the 3D printing of adipose-derived stem cells was a research team at the University of Louisville. Their study focused on one of the body's core organs, the heart. In 2014, the team printed out human heart valves and tiny blood vessels using adipose stem cells and successfully transplanted them into mice. In the next three to five years, the team will also gradually print the various components of the heart, eventually forming a complete heart and use it for human transplantation.

The traditional view is that a major cause of long-term survival of 3D-printed tissues and organs is the failure of the internal vascular system. However, with the efforts of our scientists, we have used adipose stem cells to successfully print a section of the abdominal aorta in 2016 and transplant it successfully in rhesus monkeys. In the next five to ten years, this type of 3D-printed artificial blood vessel is expected to achieve clinical application.

In addition to the replacement of internal organs and internal tissues, adipose stem cells can also be printed in 3D as facial organs to bring happiness to people with disabilities. In January 2017, scientists from the United States and the United Kingdom worked together to use 3D printers to treat adult adipose stem cells as ears for adults, creating new hope for rehabilitation for patients with congenital small ear deformities. In addition, adipose stem cells can also be used for the treatment of defects in the nose, hip joints, knee joints, etc. In the future, humans will realize the random replacement of organs.

Fat is a huge gold mine that has been misunderstood and rejected by many people, and 3D printing has fully explored its potential value. The increasingly close integration of adipose stem cells with 3D printing technology will bring huge benefits to human health.

(Editor)

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